Travatan-Z is one of the most trusted and reliable brand names of ophthalmic solution Travoprost. Travoprost is a synthetic analogue of prostaglandin F and commonly prescribed for the reduction of intraocular pressure in patients of open angle glaucoma and ocular hypertension. Travatan-Zhelps to maintain right intra ocular pressure by regulating the flow of fluids within the eye. The significance of maintaining or lowering intra ocular pressure is that it can help to prevent eye blindness and optic nerve damage.
How does Travatan-Z work?
According to the proposed mechanism of action, Travatan-Z is an isopropyl ester prodrug that is rapidly hydrolyzed by the esterases in the cornea. The generated Travoprost free acid is biologically active and a potent agonist of FP prostanoid receptor. FP receptor agonists reduce intraocular tension by increasing the outflow of aqueous humor.
A Few Of the Concerns With The Use Of Travatan-Z
Travatan-Z can lead to the permanent or irreversible darkening of the iris of the eye. Darkening of skin around the eye, thickening of eyelashes are the other but reversible concerns for the patients using this medication. Ocular hyperemia, redness of the eye is another common concern. Also, there are some potential concerns associated with it’s use in patients under the age of 15 years.
Serious Systemic effects Of Travatan-Z
Travatan-Z And Pregnancy
Like other FP agonists Travatan-Z also interferes with the maintenance of pregnancy. Thus, it’s use is strictly prohibited during pregnancy.
Clinical studies of Travatan-Z have shown that it can prove to be teratogenic at certain higher doses and can lead to some severe malformations in the foetus.
Effective Drug Dosage
The recommended dosage for Travatan-Z is a single drop of the opthalamic solution in the affected eye and commonly during the evening time. Frequent administration of Travatan-Z can reduce it’s effectiveness to reduce the intra ocular pressure. Also, the patient should ensure that he/she is not allergic to one or the other component of the drug. Share YOUR experiences with this treatment below.